Defining the Chronic Complexities of hEDS and HSD: A Global Survey of Diagnostic Challenges, Life-Long Comorbidities, and Unmet Needs

This global survey provides the most comprehensive epidemiological profile to date of individuals with hypermobile Ehlers–Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSDs), revealing a strikingly high burden of multisystemic comorbidities, profound diagnostic delays, and significant unmet clinical needs.